BioDay is a prospective multicentre registry following patients being treated with new systemic therapies. The efficacy, safety and patient satisfaction of these new systemic agents will be investigated within the registry.
The BioDay registry is coordinated by the National Expert Centre for Constitutional Eczema, University Medical Centre Utrecht (UMCU) and the Department of Dermatology, University Medical Centre Groningen (UMCG). Several other academic and non-academic centers within the Netherlands are also affiliated with the BioDay registry.
Participation in the BioDay registry is open to dermatology departments in academic and non-academic hospitals with experience in difficult-to-treat atopic dermatitis (as defined by the Dutch Quality Criteria for Eczema Care).
If you are a centre interested in being part of the BioDay registry, please contact us. If you wish to participate in the BioDay registry, an initiation visit will be arranged by the research team at the UMCU or the UMCG. During this initiation visit, the study protocol to be followed, the performance of clinical assessments and the administration of various patient questionnaires will be explained. Standard texts for the EPD will be shared. This will ensure appropriate data collection. The data will be collected for a minimum of 5 years.
Biologicals
Dupilumab - since October 2017
Tralokinumab - since November 2021
Lebrikizumab - since December 2024
JAK inhibitors
Baricitinib - as of January 2021
Upadacitinib - as of October 2021
Abrocitinib - since March 2022
In addition to primary outcome measures, such as efficacy and safety of the new systemic agents, additional research is being conducted on the impact of these drugs on:
The BioDay study protocol has been approved by the Medical Ethics Committee of the University Medical Center Utrecht and follows Good Clinical Practice guidelines.
The BioDay registry is also registered with ClinicalTrials.gov.
All participants will be informed in writing and verbally about the implications of their participation in the BioDay registry. If the patient decides to take part, he/she will have to sign an informed consent form. Data collection for the registry will be in accordance with all applicable confidentiality requirements and data protection and privacy legislation. In each participating hospital, consent will be obtained from the local medical ethics review committee and/or board of directors in accordance with local policy.
The BioDay Registry is financially supported by Sanofi/Regeneron, Abbvie, Lilly and LEO Pharma. They do not have access to the personal data of the trial participants, nor do they have any influence on the processing and publication of the trial data.
Scientific publications resulting from data from the BioDay registry appear with some regularity.
Below is an overview of publications to date.
Van der Gang, et al.
Vroman, et al.
Vroman, et al.
Van der Rijst, et al.
van der Rijst et al.
Van der Gang, et al.
Van der Rijst, et al.
van der Rijst & Velduis, et al.
Boesjes, et al.
Dekker, et al.
Dekker, et al.
van der Rijst, et al.
van der Rijst, et al.
van der Rijst, et al.
Kamphuis, et al.
Boesjes, et al.
Boesjes, et al.
van der Rijst, et al.
Dekkers, et al.
Spekhorst, et al.
Dekkers, et al.
Achten, et al.
Achten, et al.
Achten, et al.
Boesjes, et al.
Boesjes, et al.
Achten, et al.
Kamphuis, et al.
Spekhorst, et al.
Achten, et al.
Kamphuis, et al.
Boesjes, et al.
Spekhorst, et al.
Spekhorst, et al.
Spekhorst, et al.
Spekhorst, et al.
Achten, et al.
Achten, et al.
Ariëns, et al.
Oosterhaven, et al.
Bakker, et al.
Bakker, et al.
Achten, et al.
Ariëns, et al.
Spekhorst, et al.
Ariëns, et al.
De Beer, et al.
Oosterhaven, et al.
Bakker, et al.
| Cookie | Duration | Description |
|---|---|---|
| cookielawinfo-checkbox-analytics | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics". |
| cookielawinfo-checkbox-functional | 11 months | The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". |
| cookielawinfo-checkbox-necessary | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary". |
| cookielawinfo-checkbox-others | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. |
| cookielawinfo-checkbox-performance | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance". |
| viewed_cookie_policy | 11 months | The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data. |